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Pathways

Signaling pathways
List of proteins
- All proteins
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Home > Pathways > List of proteins > All proteins

spacerAll proteins

Proteins and specific areas of DNA in pathways of this website are arranged in alphabetical order. Clicking a protein provides you description of the protein with the links for it. To show a pathway including the protein, please click the pathway name in square brackets.

#: a | b | c | d | e | f | g | h | i | j | k | l | m | n | o | p | q | r | s | t | u | v | w | x | y | z | | Top |
14-3-3 [ EGF , GPCR ]
2-chimaerin [ PiP-signal ]
26 proteasome [ IL-1 , EGF ]
a: # | b | c | d | e | f | g | h | i | j | k | l | m | n | o | p | q | r | s | t | u | v | w | x | y | z | | Top |
Abi1/E3b1 [ GTPase ]
adenylyl cyclase [ G-protein ]
ADP [ IGF-1 , EGF , Ca-signaling , EGFR , GPCR , transcriptional reactions ]
ADPR [ Ca-signaling ]
Akt [ PDGF , IGF-1 , EGF ]
AMPK (AMP-activated protein kinase) [ PDGF , IGF-1 , EGF ]
AP-1 [c-Fos/c-Jun] (activator protein 1) [ IL-1 , IL-6 ]
Apaf-1 [ apoptosis ]
APRE (AMP-activated protein kinase) [ IL-1 , IL-6 ]
ATP [ G-protein , IGF-1 , EGF , Ca-signaling , EGFR , GPCR , PKA , transcriptional reactions ]
b: # | a | c | d | e | f | g | h | i | j | k | l | m | n | o | p | q | r | s | t | u | v | w | x | y | z | | Top |
Bad [ EGF , apoptosis ]
Bax [ apoptosis ]
Bcl-2 [ EGF , apoptosis ]
Bcl-XL [ apoptosis ]
Bid [ apoptosis ]
Bid terminal [ apoptosis ]
Bim [ apoptosis ]
c: # | a | b | d | e | f | g | h | i | j | k | l | m | n | o | p | q | r | s | t | u | v | w | x | y | z | | Top |
c-Cbl [ endocytosis ]
c-Fos [ IL-1 , IL-3 , IL-6 , transcriptional reactions ]
c-Jnn [ transcriptional reactions ]
c-Jun [ IL-1 , IL-6 , transcriptional reactions ]
c-Myc [ transcriptional reactions ]
c-Src [ EGFR , endocytosis , MAPK ]
cADPR [ Ca-signaling ]
Calpain [ PKA ]
CaM (cell adhesion molecule) [ G-protein , Ca-signaling , GPCR ]
CaMKII [ Ca-signaling ]
cAMP [ G-protein , PKA ]
caspase-3 [ apoptosis ]
caspase-8 [ apoptosis ]
caspase-9 [ apoptosis ]
CBP (CREB binding protein) [ TGF-beta ]
CD38 [ Ca-signaling ]
Cdc42 [ EGFR , GTPase , MAPK ]
CKⅡ (casein kinase II) [ IL-1 , IL-6 , PDGF ]
CN [ G-protein ]
CRE (C-reactive protein) [ G-protein , IL-6 , IL-1 ]
CREB (cAMP response element-binding protein) [ G-protein , TPO , EGF , transcriptional reactions ]
CrkL [ TPO ]
cytochrome c [ EGF , apoptosis ]
d: # | a | b | c | e | f | g | h | i | j | k | l | m | n | o | p | q | r | s | t | u | v | w | x | y | z | | Top |
dADP/ADP [ apoptosis ]
dADP/ATP [ apoptosis ]
DAG (diacylglycerol) [ G-protein , PDGF , PiP-signal ]
DD [ apoptosis ]
DED [ apoptosis ]
DFF [ apoptosis ]
DFF40 [ apoptosis ]
DFF45 [ apoptosis ]
e: # | a | b | c | d | f | g | h | i | j | k | l | m | n | o | p | q | r | s | t | u | v | w | x | y | z | | Top |
EBS [ IL-6 , PDGF ]
EGF [ EGF , EGFR , endocytosis , GTPase , PiP-signal ]
EGFR [ EGF , EGFR , endocytosis , GTPase ]
elF (eukaryotic translation initiation factor) [ IGF-1 ]
elF-4E [ EGF ]
Elk-1 (ETS-like kinase protein-1) [ G-protein , IL-1 , IL-6 , IGF-1 , transcriptional reactions ]
Eps8 [ GTPase ]
ER (endoplasmic reticulum) [ G-protein ]
ERK (extracellular signal-regulated kinase) [ G-protein , IL-6 , PDGF , IGF-1 , TPO , IL-3 , IL-1 ]
ERK1 [ GTPase , MAPK , transcriptional reactions ]
ERK2 [ GTPase , MAPK ]
f: # | a | b | c | d | e | g | h | i | j | k | l | m | n | o | p | q | r | s | t | u | v | w | x | y | z | | Top |
Fas ligand [ EGF , apoptosis ]
Fas ligand trimer [ apoptosis ]
Fas Receptor [ apoptosis ]
FKBP [ Ca-signaling ]
g: # | a | b | c | d | e | f | h | i | j | k | l | m | n | o | p | q | r | s | t | u | v | w | x | y | z | | Top |
Gab1 [ EGF , EGFR , PiP-signal ]
GAP (GTPase activating protein) [ IL-6 , PDGF , TPO , IGF-1 ]
GDP (guanosine diphosphate) [ G-protein , IL-3 , IL-6 , IGF-1 , TPO , EGF , GPCR , GTPase , PKA ]
gp130 (glycoprotein 130) [ IL-6 ]
Grb2 (growth factor receptor binding protein 2) [ IL-3 , IL-6 , IGF-1 , TPO , EGF , GTPase , MAPK ]
GSP [ PDGF ]
GTP (guanosine triphosphate) [ G-protein , IL-3 , IL-6 , PDGF , IGF-1 , TPO , EGF , EGFR , GPCR , GTPase , MAPK , PKA ]
i/o (G alpha i/o) [ G-protein ]
Gα 12/13 (G alpha 12/13) [ GPCR , PKA ]
Gα 5 (G alpha 5) [ PKA ]
i/o Gβγ -coupled receptor (G alpha i/o G beta gamma -coupled receptor) [ G-protein ]
q (G alpha q) [ G-protein , GPCR ]
q-coupled receptor (G alpha q-coupled receptor) [ G-protein ]
s (G alpha s) [ G-protein ]
Gβγ (G beta gamma) [ G-protein , GPCR , PKA ]
h: # | a | b | c | d | e | f | g | i | j | k | l | m | n | o | p | q | r | s | t | u | v | w | x | y | z | | Top |
HB-EGF [ EGFR ]
Hck [ IL-6 ]
HCP [ IL-3 ]
hSIE [ TPO ]
i: # | a | b | c | d | e | f | g | h | j | k | l | m | n | o | p | q | r | s | t | u | v | w | x | y | z | | Top |
IGF-1 (insulin-like growth factor-1) [ IGF-1 ]
IGF-IR α (insulin-like growth factor-IR alpha) [ IGF-1 ]
IGF-IR β (insulin-like growth factor-IR beta) [ IGF-1 ]
IKK (IkB kinase) [ IL-1 ]
IKK complex [ EGF ]
IL-1 (Interleukin-1) [ IL-1 ]
IL-1RAcP (Interleukin-1 receptor accessory protein) [ IL-1 ]
IL-1RI [ IL-1 ]
IL-3 (Interleukin-3) [ IL-3 ]
IL-3R α (Interleukin-3R alpha) [ IL-3 ]
IL-3R β (Interleukin-3R beta) [ IL-3 ]
IL-6 (Interleukin-6) [ IL-6 ]
IL-6R (IL-6 receptor) [ IL-6 ]
IL-6RE [ IL-1 , IL-6 ]
IP3 (inositol 1,4,5-trisphosphate) [ G-protein , PDGF , EGF , Ca-signaling , PiP-signal ]
IP3R [ Ca-signaling ]
IRAK1 (Interleukin-1 receptor-associated kinase 1) [ IL-1 ]
IRAK4 (Interleukin-1 receptor-associated kinase 4) [ IL-1 ]
IRS (insulin receptor substrate) [ IGF-1 ]
IκB (inhibitory kappa B) [ IL-1 ]
j: # | a | b | c | d | e | f | g | h | i | k | l | m | n | o | p | q | r | s | t | u | v | w | x | y | z | | Top |
JAKS [JAK1,JAK2,Tyk1] [ IL-6 ]
JAK2 (Janus kinase 2) [ IL-3 , TPO ]
JNK (c-Jun N-terminal kinase) [ IL-1 , MAPK , transcriptional reactions ]
k: # | a | b | c | d | e | f | g | h | i | j | l | m | n | o | p | q | r | s | t | u | v | w | x | y | z | | Top |
KDI1 [ EGFR , GTPase ]
l: # | a | b | c | d | e | f | g | h | i | j | k | m | n | o | p | q | r | s | t | u | v | w | x | y | z | | Top |
LARG [ PKA ]
ligand [ G-protein ]
LKB1 [ PDGF , IGF-1 ]
LPA/PGE2 [ GPCR ]
m: # | a | b | c | d | e | f | g | h | i | j | k | l | n | o | p | q | r | s | t | u | v | w | x | y | z | | Top |
MAPK (MAP kinases: mitogen-activated protein kinases) [ MAPK ]
MAPKK (MAP kinase kinase: mitogen-activated protein kinase kinase) [ MAPK ]
MDM2 [ EGF ]
MEF-2C (myocyte enhancer factor-2C) [ IL-1 , IL-6 ]
MEK (MAPK/ERK kinase) [ G-protein , IL-6 , PDGF , IGF-1 , TPO , IL-3 , IL-1 ]
MEKK1 [ MAPK ]
MK2 [ IL-1 , IL-6 ]
MKK1 [ MAPK ]
MKK2 [ MAPK ]
MKK3 (MAP kinase kinase 3) [ IL-1 , MAPK ]
MKK4 (MAP kinase kinase 4) [ IL-1 , MAPK ]
MKK6 (MAP kinase kinase 6) [ IL-1 , MAPK ]
MKK7 (MAP kinase kinase 7) [ IL-1 , MAPK ]
MKP [ transcriptional reactions ]
MLK3 [ MAPK ]
mLST8 [ PDGF , IGF-1 ]
Mpl (TPO receptor) [ TPO ]
mRNA [ PDGF , IGF-1 , EGF ]
mTOR (mammalian target of rapamycin) [ PDGF , IGF-1 , EGF ]
MyD88 (myeloid differentiation primary response gene 88) [ IL-1 ]
n: # | a | b | c | d | e | f | g | h | i | j | k | l | m | o | p | q | r | s | t | u | v | w | x | y | z | | Top |
NaD+ [ Ca-signaling ]
NF-IL-6 [ IL-1 , IL-6 ]
NF-κB (nuclear factor-kappa B) [ IL-1 , EGF ]
NFAT-RE [ G-protein ]
NFATc [ G-protein ]
o: # | a | b | c | d | e | f | g | h | i | j | k | l | m | n | p | q | r | s | t | u | v | w | x | y | z | | Top |
p: # | a | b | c | d | e | f | g | h | i | j | k | l | m | n | o | q | r | s | t | u | v | w | x | y | z | | Top |
p110 [ PiP-signal ]
p300 [ TGF-beta ]
p300/CBP [ TGF-beta ]
p38 [ IL-1 ]
P38MAPK [ MAPK ]
p53 [ EGF ]
p73 [ EGF ]
p85 [ PiP-signal ]
PAK1 [ EGFR , MAPK ]
PDGF (platelet-derived growth factor) [ PDGF ]
PDGFR-α (platelet-derived growth factor receptor-alpha) [ PDGF ]
PDGFR-β (platelet-derived growth factor receptor-beta) [ PDGF ]
PDK (phosphoinositide-dependent kinase) [ PDGF , IGF-1 ]
PDK1 [ transcriptional reactions , PiP-signal ]
PI3,4-P2 [ PiP-signal ]
PI3,4,5-P2 [ PiP-signal ]
PI3K (phosphoinositide 3-kinase) [ PDGF , IGF-1 , EGF , GTPase , PiP-signal ]
PI4-P [ PiP-signal ]
PI4,5-P2 [ PiP-signal ]
PI5K [ PiP-signal ]
PIP2 (phophatidylinositol 3,4-bisphophste) [ G-protein , PDGF , IGF-1 , EGF ]
PIP3 (phosphatidylinositol 3,4,5-trisphosphate) [ PDGF , IGF-1 , EGF ]
PKA [ G-protein , Ca-signaling , PKA ]
PKB/Akt [ MAPK , PiP-signal ]
PKC (protein kinase C) [ G-protein , PDGF , endocytosis , PKA , PiP-signal ]
PLC (phospholipase C) [ G-protein , PDGF , EGFR ]
PLD [ PKA ]
PP2 [ EGFR ]
PP2A [ Ca-signaling , transcriptional reactions , PiP-signal ]
PP2B [ transcriptional reactions ]
PPI [ Ca-signaling ]
pro HB-EDF [ EGFR ]
procaspase-3 [ apoptosis ]
procaspase-9 [ apoptosis ]
PTEN (phosphatase and tensin homologue deleted on chromosome ten) [ PDGF , IGF-1 , PiP-signal ]
Pyk2 [ EGFR ]
q: # | a | b | c | d | e | f | g | h | i | j | k | l | m | n | o | p | r | s | t | u | v | w | x | y | z | | Top |
r: # | a | b | c | d | e | f | g | h | i | j | k | l | m | n | o | p | q | s | t | u | v | w | x | y | z | | Top |
R [ PKA ]
R-Smad (receptor-regulated Smad) [ TGF-beta ]
Rab5a [ endocytosis , GTPase ]
Rac [ EGFR , GTPase , MAPK ]
Raf-1 [ G-protein , IL-3 , IL-6 , PDGF , IGF-1 , TPO , MAPK ]
raptor (regulatory associated protein of mTOR) [ PDGF , IGF-1 , EGF ]
Ras [ GTPase , MAPK ]
Ras-GDP [ G-protein , IL-6 , PDGF , IGF-1 , TPO , IL-1 ]
Ras-GTP [ G-protein , IL-6 , PDGF , IGF-1 , TPO , IL-1 ]
RGS4 [ GPCR ]
RGS7 [ GPCR ]
Rheb-GDP [ PDGF , IGF-1 , EGF ]
Rheb-GTP [ PDGF , IGF-1 , EGF ]
RhoA [ PKA ]
Rin1 [ GTPase ]
RN-tre [ GTPase ]
RSK (protein of 90-kDa ribosomal S6 kinase) [ TPO ]
RSK2 [ G-protein , GTPase , transcriptional reactions ]
RYR [ Ca-signaling ]
s: # | a | b | c | d | e | f | g | h | i | j | k | l | m | n | o | p | q | r | t | u | v | w | x | y | z | | Top |
S1P/LPA [ GPCR ]
S1P/LPA/PGE2 [ GPCR ]
S5RE (Stat5 responsive element) [ TPO ]
S6K [ EGF ]
S6K1 (p70S6 kinase) [ PDGF , IGF-1 ]
SARA (Smad anchor for receptor activation) [ TGF-beta ]
SBE (Smad-binding element) [ TGF-beta ]
SERCA [ Ca-signaling ]
Shc (Src-homology collagren protein) [ IGF-1 , IL-3 , IL-6 , PDGF , TPO , GTPase ]
SHIP2 [ PiP-signal ]
Shp-2 (SH2 domain-containing protein tyrosine phosphatase 2) [ IL-6 ]
SHP-2 (Src homology containing phosphatase-2) [ PDGF ]
SHP1 [ endocytosis ]
SHP2 [ EGFR ]
SIE [ PDGF ]
Ski [ TGF-beta ]
Ski/SnoN [ TGF-beta ]
Smad4 (Sma and Mad [mothers against decapentaplegic] homologue 4) [ TGF-beta ]
Smad7 (Sma and Mad [mothers against decapentaplegic] homologue 7) [ TGF-beta ]
Smurf1 (Smad ubiquitination regulatory factor 1) [ TGF-beta ]
Smurf2 (Smad ubiquitination regulatory factor 2) [ TGF-beta ]
SnoN [ TGF-beta ]
Sos (Son of sevenless) [ IL-3 , IGF-1 , TPO ]
SOS-1 (Son of sevenless-1) [ IL-6 , PDGF , endocytosis , GTPase ]
SPRY2 [ endocytosis ]
Src [ PDGF ]
SRE (serum response element) [ G-protein , PDGF , IL-6 , IL-1 ]
SRF (serum response factor) [ IL-6 , PDGF , IL-1 ]
STAT1 (signal transducers and activators of transcription 1) [ TPO , PDGF , IL-6 , EGFR ]
STAT3 (signal transducers and activators of transcription 3) [ TPO , IL-6 , EGFR ]
STAT5 (signal transducers and activators of transcription 5) [ IL-3 ]
STAT5a (signal transducers and activators of transcrition 5a) [ TPO ]
STAT5b (signal transducers and activators of transcription 5b) [ TPO ]
t: # | a | b | c | d | e | f | g | h | i | j | k | l | m | n | o | p | q | r | s | u | v | w | x | y | z | | Top |
t-PLC [ PKA , PiP-signal ]
TAB1 (TKA1 binding protein 1) [ IL-1 ]
TAB2 (TKA1 binding protein 2) [ IL-1 ]
TAK1 (TGF-beta-activated kinase 1) [ IL-1 ]
TGF-β (transforming growth factor-beta) [ TGF-beta ]
TGF-β receptor type I (transforming growth factor-beta receptor type I) [ TGF-beta ]
TGF-β receptor type II (transforming growth factor-beta receptor type II) [ TGF-beta ]
Tollip (Toll-interacting protein) [ IL-1 ]
TPO (Thrombopoietin) [ TPO ]
TRAF6 (tumor necrosis factor receptor-associated factor 6) [ IL-1 ]
TRE (TPA response elements) [ IL-1 , IL-3 , IL-6 ]
TSC1 (tuberous sclerosis complex 1) [ PDGF , IGF-1 ]
TSC2 (tuberous sclerosis complex 2) [ PDGF , IGF-1 , EGF ]
u: # | a | b | c | d | e | f | g | h | i | j | k | l | m | n | o | p | q | r | s | t | v | w | x | y | z | | Top |
Ubc-H7 [ endocytosis ]
Ubc13 [ IL-1 ]
Uev1A [ IL-1 ]
v: # | a | b | c | d | e | f | g | h | i | j | k | l | m | n | o | p | q | r | s | t | u | w | x | y | z | | Top |
Vav2 [ EGFR ]
w: # | a | b | c | d | e | f | g | h | i | j | k | l | m | n | o | p | q | r | s | t | u | v | x | y | z | | Top |
x: # | a | b | c | d | e | f | g | h | i | j | k | l | m | n | o | p | q | r | s | t | u | v | w | y | z | | Top |
XBE (X-binding element) [ TGF-beta ]
y: # | a | b | c | d | e | f | g | h | i | j | k | l | m | n | o | p | q | r | s | t | u | v | w | x | z | | Top |
YAP [ EGF ]
z: # | a | b | c | d | e | f | g | h | i | j | k | l | m | n | o | p | q | r | s | t | u | v | w | x | y | | Top |