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Pathways

Signaling pathways
List of proteins
References
- Alphabetical order
- Chronological order
- Used for pathways

Home > Pathways > References > Alphabetical order

spacerAlphabetical order

References used for pathways are arranged in alphabetical order of the first author's family name. Clicking a reference brings you to the corresponding PubMed page. To show a pathway referring the paper, please click the pathway name in parentheses.

A: B | C | D | E | F | G | H | I | J | K | L | M | N | O | P | Q | R | S | T | U | V | W | X | Y | Z | URL | | Top |

Alberts, B., Johnson, A., Lewis, J., Raff, M., Roberts, K. and Walter, P., Molecular Biology of the Cell -fourth edition-, pp.871-872, 2002. ( IGF-1 )

Alberts, B.,, Johnson, A., Lewis, J., Raff, M., Roberts, K. and Walter, P., Molecular Biology of the Cell -fourth edition-, pp.878-879 2002. ( IL-6 )

Albrecht, C., Borm, P. J. and Unfried, K., Signal transduction pathways relevant for neoplastic effects of fibrous and non-fibrous particles, Mutation research, 553(1-2), pp.23-35, 2004. ( IL-1 )

Alexander, W. S., Thrombopoietin and the c-Mpl receptor: insights from gene targeting, The International Journal of Biochemistry & Cell Biology, 31(10), pp.1027-1035, 1999. ( TPO )

Arzt, E., gp130 cytokine signaling in the pituitary gland: a paradigm for cytokine-neuro-endocrine pathways, The Journal of Clinical Investigation, 108(12), pp.1729-33, 2001. ( IL-6 )

Auernhammer, C. J., Zitzmann, K., Schnitzler, F., Seiderer, J., Lohse, P., Vlotides, G., Engelhardt, D., Sackmann, M., Goke, B. and Ochsenkuhn, T., Role of the intracellular receptor domain of gp130 (exon 17) in human inflammatory bowel disease, World journal of gastroenterology 11(8), pp.1196-1199, 2005. ( IL-6 )

B: A | C | D | E | F | G | H | I | J | K | L | M | N | O | P | Q | R | S | T | U | V | W | X | Y | Z | URL | | Top |

Ballou, L. M., Jiang, Y. P., Du, G., Frohman, M. A. and Lin, R. Z., Ca(2+)- and phospholipase D-dependent and ?independent pathways activate mTOR signaling, FEBS letters, 550(1-3), 51-56, 2003. ( PDGF )

Bartoe, J. L. and Nathanson, N. M., Independent roles of SOCS-3 and SHP-2 in the regulation of neuronal gene expression by leukemia inhibitory factor, Brain research. Molecular brain research, 107(2), pp.108-119, 2002. ( IL-6 )

Berenbaum, F., Proinflammatory cytokines, prostaglandins, and the chondrocyte:mechanisms of intracellular activation, Joint, bone, spine:revue du rhumatisme, 67(6) pp.561-564, 2000. ( IL-1 )

Bird, T. A., Schooley, K., Dower, S. K., Hagen, H. and Virca, G. D., Activation of nuclear transcription factor NF-kappaB by interleukin-1 is accompanied by casein kinase II-mediated phosphorylation of the p65 subunit, The Journal of biological chemistry, 272(51), pp.32606-32612, 1997. ( IL-1 )

Blaukat, A., Barac, A., Cross, M. J., Offermanns, S. and Dikic, I., G protein-coupled receptor-mediated mitogen-activated protein kinase activation through cooperation of Galpha(q) and Galpha(i) signals, Molecular and cellular biology, 20(18), pp.6837-6848, 2000. ( G-protein )

Bonizzi, G. and Karin, M., The two NF-kappaB activation pathways and their role in innate and adaptive immunity, Trends in immunology, 25(6), pp.280-288, 2004. ( IL-1 )

Burke, L. J. and Baniahmad, A., Co-repressors 2000, The FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 14(13), pp.1876-1888, 2000. ( TGF-beta )

C: A | B | D | E | F | G | H | I | J | K | L | M | N | O | P | Q | R | S | T | U | V | W | X | Y | Z | URL | | Top |

Carter, A. B., Monick, M. M. and Hunninghake, G. W., Both Erk and p38 kinases are necessary for cytokine gene transcription, American journal of respiratory cell and molecular biology, 20(4), pp.751-758, 1999. ( IL-6 )

Chastel, C., Jiricny, J. and Jaussi, R., Activation of stress-responsive promoters by ionizing radiation for deployment in targeted gene therapy, DNA repair, 3(3), pp.201-215, 2004. ( IL-1 )

Chen, W., Daines, M. O. and Khurana Hershey G. K., Turning off signal transducer and activator of transcription (STAT): the negative regulation of STAT signalng, The Journal of allergy and clinical immunology, 114(3), pp.476-489,quiz 490, 2004. ( IL-3 )

Chow, D. C., Brevnova, L., He, X. L., Martick, M. M., Bankovich, A. and Garcia, K. C., A structural template for gp130-cytokine signaling assemblies, Biochimica et biophysica acta, 1592(3), pp.225-235, 2002. ( IL-6 )

Cirri, P., Chiarugi, P., Marra, F., Raugei, G., Camici, G., Manao, G. and Ramponi, G., c-Src activates both STAT1 and STAT3 in PDGF-stimulated NIH3T3 cells, Biochemical and Biophysical Research Communications, 239(2) pp.493-497, 1997. ( PDGF )

Crabtree, G. R. and Olson, E. N., NFAT signaling: choreographing the social lives of cells, Cell, 109 Suppl, S67-79, 2002. ( G-protein )

D: A | B | C | E | F | G | H | I | J | K | L | M | N | O | P | Q | R | S | T | U | V | W | X | Y | Z | URL | | Top |

da Rocha, A. B., Mans, D. R., Regner, A. and Schwartsmann G., Targeting protein kinase C: new therapeutic opportunities against high-grade malignant gliomas?, The oncologist, 7(1), pp.17-33, 2002. ( PDGF )

de Groot, R. P., Coffer, P. J. and Koenderman, L., Regulation of proliferation, differentiation and survival by the IL-3/IL-5/GM-CSF receptor family, Cellular signalling, 10(9), pp.619-628, 1998. ( IL-3 )

Derynck, R. and Zhang, Y. E., Smad-dependent and Smad-independent pathways in TGF-beta family signalling, Nature, 425(6958), pp.577-584, 2003. ( TGF-beta )

Dixit, V. and Mak, T. W., NF-kappaB signaling. Many roads lead to madrid, Cell, 111(5), pp.615-619, 2002. ( IL-1 )

Dremier, S., Kopperud, R., Doskeland, S. O., Dumont, J. E. and Maenhaut, C., Search for new cyclic AMP-binding proteins, FEBS letters, 546(1), pp.103-107, 2003. ( G-protein )

Dupont, J. and Holzenberger, M., Biology of insulin-like growth factors in development, Birth Defects & Research, 69(4), pp.257-271, 2003. ( IGF-1 )

E: A | B | C | D | F | G | H | I | J | K | L | M | N | O | P | Q | R | S | T | U | V | W | X | Y | Z | URL | | Top |

Eferl, R. and Wagner, E. F., AP-1: a double-edged sword in tumorigenesis, Nature reviews. Cancer, 3(11), pp.859-868, 2003. ( IL-1 )

Ernst, M. and Jenkins, B. J., Acquiring signalling specificity from the cytokine receptor gp130, Trends in genetics, 20(1), pp.23-32, 2004. ( IL-6 )

F: A | B | C | D | E | G | H | I | J | K | L | M | N | O | P | Q | R | S | T | U | V | W | X | Y | Z | URL | | Top |

Finley, D., Signal transduction. An alternative to destruction, Nature, 412(6844), pp.283, 285-286, 2001. ( IL-1 )

Fresno Vara, J. A., Casado, E., de Castro, J., Cejas, P., Belda-Iniesta, C. and Gonzalez-Baron, M., PI3K/Akt signalling pathway and cancer, Cancer treatment reviews, 30(2), pp.193-204, 2004. ( PDGF , IGF-1 )

Frodin, M., Jensen, C. J., Merienne, K. and Gammeltoft, S., A phosphoserine-regulated docking site in the protein kinase RSK2 that recruits and activates PDK1, The EMBO journal, 19(12), pp.2924-2934, 2000. ( G-protein )

Fujimoto, M. and Naka, T., Regulation of cytokine signaling by SOCS family molecules, Trends in immunology, 24(12), pp.659-66, 2003. ( IL-6 )

G: A | B | C | D | E | F | H | I | J | K | L | M | N | O | P | Q | R | S | T | U | V | W | X | Y | Z | URL | | Top |

Geddis, A. E., Linden, H. M. and Kaushansky, K., Thrombopoietin: a pan-hematopoietic cytokine, Cytokine & Growth Factor Reviews, 13(1), pp.61-73, 2002. ( TPO )

Gingras, A. C., Raught, B. and Sonenberg, N., Regulation of translation initiation by FRAP/mTOR, Genes & development, 15(7) pp.807-826, 2001. ( PDGF , IGF-1 )

Girnita, L., Girnita, A. and Larsson, O., Mdm2-dependent ubiquitination and degradation of the insulin-like growth factor 1 receptor, Proceedings of the National Academy of Sciences of the United States of America, 100(14) pp.8247-8252, 2003. ( IGF-1 )

H: A | B | C | D | E | F | G | I | J | K | L | M | N | O | P | Q | R | S | T | U | V | W | X | Y | Z | URL | | Top |

Hanlon, M., Bundy, L. M. and Sealy, L., C/EBP beta and Elk-1 synergistically transactivate the c-fos serum response element, BMC cell biology [electronic resource], 1:2 2000. ( IL-1 )

Hara, K., Maruki, Y., Long, X., Yoshino, K., Oshiro, N., Hidayat, S., Tokunaga, C., Avruch, J. and Yonezawa, K., Raptor, a binding partner of target of rapamycin (TOR), mediates TOR action, Cell, 110(2) pp.177-189, 2002. ( PDGF , IGF-1 )

Hardie, D. G., New roles for the LKB1-->AMPK pathway, Current Opinion in Cell Biology, 17(2), pp.167-173, 2005. ( PDGF , IGF-1 )

Harrington, L. S., Findlay, G. M., Gray, A., Tolkacheva, T., Wigfield, S., Rebholz, H., Barnett, J., Leslie, N. R., Cheng, S., Shepherd, P. R.,Gout, I., Downes, C. P. and Lamb, R. F., The TSC1-2 tumor suppressor controls insulin-PI3K signaling via regulation of IRS proteins, The Journal of Cell Biology, 166(2), pp.213-223, 2004. ( IGF-1 )

Hawes, B. E., van Biesen, T., Koch, W. J., Luttrell, L. M. and Lefkowitz, R. J., Distinct pathways of Gi- and Gq-mediated mitogen-activated protein kinase activation, The Journal of biological chemistry, 270(29), pp.17148-17153, 1995. ( G-protein )

Heinlein, C. A. and Chang, C., Signal Transduction Pathways Modulate Androgen Receptor Transcriptional Activity, Androgens and Androgen Receptor: Mechanisms, Functions, and Clinical Applications, Kluwer Academic Publishing, USA, pp.57-90, 2002. ( IL-6 )

Heinrich, P. C., Behrmann, I., Haan, S., Hermanns, H. M., Muller-Newen, G. and Schaper, F., Principles of interleukin (IL)-6-type cytokine signalling and its regulation, The Biochemical journal, 374(Pt 1), pp.1-20, 2003. ( IL-6 )

Heinrich, P. C., Behrmann,I., Muller-Newen, G., Schaper, F. and Graeve, L., Interleukin-6-type cytokine signalling through the gp130/Jak/STAT pathway, The Biochemical journal, 334(Pt 2), pp.297-314, 1998. ( IL-6 )

Heldin, C. H., Simultaneous induction of stimulatory and inhibitory signals by PDGF, FEBS letters, 410(1), pp.17-21, 1997. ( PDGF )

Heldin, C. H., Ostman, A., Ronnstrand, L., Signal transduction via platelet-derived growth factor receptors, Biochimica et biophysica acta, 1378(1), pp.F79-F113, 1998. ( PDGF )

Herlaar, E. and Brown, Z., p38 MAPK signalling cascades in inflammatory disease, Molecular medicine today, 5(10), pp.439-447, 1999. ( IL-1 )

Hill, S. J., Baker, J. G. and Rees, S., Reptor-gene systems for the study of G-protein-coupled receptors, Current Opinion in Pharmacology, 1(5), pp.526-532, 2001. ( G-protein )

Horvath, C. M., STAT proteins and transcriptional responses to extracellular signals, Trends in biochemical sciences, 25(10), pp.496-502, 2000. ( IL-3 )

Huang, S. and Houghton, P. J., Targeting mTOR signaling for cancer therapy, Current Opinion in Pharmacology, 3(4), pp.371-377, 2003. ( PDGF , IGF-1 )

I: A | B | C | D | E | F | G | H | J | K | L | M | N | O | P | Q | R | S | T | U | V | W | X | Y | Z | URL | | Top |

Inoki, K., Li, Y., Xu, T. and Guan, K. L., Rheb GTPase is a direct target of TSC2 GAP activity and regulates mTOR signaling, Genes & development, 17(15), pp.1829-1834, 2003. ( PDGF , IGF-1 )

J: A | B | C | D | E | F | G | H | I | K | L | M | N | O | P | Q | R | S | T | U | V | W | X | Y | Z | URL | | Top |

Janssens, S. and Beyaert, R., Functional diversity and regulation of different interleukin-1 receptor-associated kinase (IRAK) family members, Molecular Cell, 11(2), pp.293-302, 2003. ( IL-1 )

Jefferies, C., Bowie, A., Brady, G., Cooke, E. L., Li, X. and O'Neill, L. A., Transactivation by the p65 subunit of NF-kappaB in response to interleukin-1 (IL-1) involves MyD88, IL-1 receptor-associated kinase 1, TRAF-6, and Rac1, Molecular and cellular biology, 21(14), pp.4544-4552, 2001. ( IL-1 )

Jensen, A. A. and Spalding, T. A., Allosteric modulation of G-protein coupled receptors, European Journal of Pharmaccutical Sciences, 21(4), pp.407-420, 2004. ( G-protein )

Jiang, Z., Ninomiya-Tsuji, J., Qian, Y., Matsumoto, K. and Li, X., Interleukin-1 (IL-1) receptor-associated kinase-dependent IL-1-induced signaling complexes phosphorylate TAK1 and TAB2 at the plasma membrane and activate TAK1 in the cytosol, Molecular and cellular biology, 22(20), pp.7158-7167, 2002. ( IL-1 )

Johannessen, M., Delghandi, M. P. and Moens, U., What turns CREB on?, Cellular Signalling, 16(11), pp.1211-1227, 2004. ( G-protein , TPO )

K: A | B | C | D | E | F | G | H | I | J | L | M | N | O | P | Q | R | S | T | U | V | W | X | Y | Z | URL | | Top |

Kanamori, M., Kai, C., Hayashizaki, Y. and Suzuki, H., NF-kappaB activator Act1 associates with IL-1/Toll pathway adaptor molecule TRAF6, FEBS Letters, 532(1-2), pp.241-246, 2002. ( IL-1 )

Kerr, I. M., Costa-Pereira, A. P., Lillemeier, B. F. and Strobl, B., Of JAKs, STATs, blind watchmakers, jeeps and trains, FEBS Letters, 546(1), pp.1-5, 2003. ( IL-6 )

Kishida, S., Sanjo, H., Akira, S., Matsumoto, K. and Ninomiya-Tsuji, J., TAK1-binding protein 2 facilitates ubiquitination of TRAF6 and assembly of TRAF6 with IKK in the IL-1 signaling pathway, Genes to cells : devoted to molecular & cellular mechanisms, 10(5), pp.447-454, 2005. ( IL-1 )

Kishimoto, K., Matsumoto, K. and Ninomiya-Tsuji, J., TAK1 mitogen-activated protein kinase kinase kinase is activated by autophosphorylation within its activation loop, The Journal of biological chemistry, 275(10), pp.7359-7364, 2000. ( IL-1 )

Kisseleva, T., Bhattacharya, S., Braunstein, J. and Schindler, C. W., Signaling through the JAK/STAT pathway, recent advances and future challenges, Gene, 285(1-2), pp.1-24, 2002. ( IL-3 )

Knight, D. A., Ernst, M., Anderson, G. P., Moodley, Y. P. and Mutsaers, S. E., The role of gp130/IL-6 cytokines in the development of pulmonary fibrosis: critical determinants of disease susceptibility and progression?, Pharmacology & therapeutics, 99(3), pp.327-338, 2003. ( IL-6 )

L: A | B | C | D | E | F | G | H | I | J | K | M | N | O | P | Q | R | S | T | U | V | W | X | Y | Z | URL | | Top |

Lehmann, U., Schmitz, J., Weissenbach, M., Sobota, R. M., Hortner, M., Friederichs, K., Behrmann, I., Tsiaris, W., Sasaki, A., Schneider-Mergener, J., Yoshimura, A., Neel, B. G., Heinrich, P. C. and Schaper, F., SHP2 and SOCS3 contribute to Tyr-759-dependent attenuation of interleukin-6 signaling through gp130, The Journal of biological chemistry, 278(1), pp.661-671, 2003. ( IL-6 )

Lin, A., Frost, J., Deng, T., Smeal, T., al-Alawi, N., Kikkawa, U., Hunter, T., Brenner, D. and Karin, M., Casein kinase II is a negative regulator of c-Jun DNA binding and AP-1 activity, Cell, 70(5), pp.777-789, 1992. ( IL-1 )

Lo, Y. Y., Luo, L., McCulloch, C. A. and Cruz, T. F., Requirements of focal adhesions and calcium fluxes for interleukin-1-induced ERK kinase activation and c-fos expression in fibroblasts, The Journal of biological chemistry, 273(12), pp.7059-65, 1998. ( IL-1 )

Luo, K., Ski and SnoN: negative regulators of TGF-beta signaling, Current opinion in genetics & development, 14(1), pp.65-70, 2004. ( TGF-beta )

M: A | B | C | D | E | F | G | H | I | J | K | L | N | O | P | Q | R | S | T | U | V | W | X | Y | Z | URL | | Top |

Martin, M. U. and Wesche, H., Summary and comparison of the signaling mechanisms of the Toll/interleukin-1 receptor family, Biochimica et biophysica acta, 1592(3), pp.265-280, 2002. ( IL-1 )

Matsushima, A., Kaisho, T., Rennert, P. D., Nakano, H., Kurosawa, K., Uchida, D., Takeda, K., Akira, S. and Matsumoto, M., Essential role of nuclear factor (NF)-kappaB-inducing kinase and inhibitor of kappaB (IkappaB) kinase alpha in NF-kappaB activation through lymphotoxin beta receptor, but not through tumor necrosis factor receptor I, The Journal of experimental medicine, 193(5), pp.631-636, 2001. ( IL-1 )

Mazzucchelli, C. and Brambilla, R., Ras-related and MAPK signalling in neuronal plasticity and memory formation, Cellular and molecular life sciences, 57(4), pp.604-611, 2000. ( G-protein )

McElhinny, J. A., Trushin, S. A., Bren, G. D., Chester, N. and Paya, C. V., Casein kinase II phosphorylates I kappa B alpha at S-283, S-289, S-293, and T-291 and is required for its degradation, Molecular and cellular biology, 16(3), pp.899-906, 1996. ( IL-1 , PDGF )

McGettrick, A. F., and O'Neill, L. A., The expanding family of MyD88-like adaptors in Toll-like receptor signal transduction, Molecular Immunology, 41(6-7), pp.577-582, 2004. ( IL-1 )

Miyazono, K., TGF-beta signaling by Smad proteins, Cytokine & growth factor reviews, 11(1-2), pp.15-22, 2000. ( TGF-beta )

Molkentin, J. D., Li, L. and Olson, E. N., Phosphorylation of the MADS-Box transcription factor MEF2C enhances its DNA binding activity, The Journal of biological chemistry, 271(29), pp.17199-17204, 1996. ( IL-1 )

N: A | B | C | D | E | F | G | H | I | J | K | L | M | O | P | Q | R | S | T | U | V | W | X | Y | Z | URL | | Top |

Naka, T., Nishimoto, N. and Kishimoto, T., The paradigm of IL-6: from basic science to medicine, Arthritis research, 4 Suppl 3, pp.S233-242, 2002. ( IL-6 )

Ninomiya-Tsuji, J., Kishimoto, K., Hiyama, A., Inoue, J., Cao, Z. and Matsumoto, K., The kinase TAK1 can activate the NIK-I kappaB as well as the MAP kinase cascade in the IL-1 signalling pathway, Nature, 398(6724), pp.252-256, 1999. ( IL-1 )

O: A | B | C | D | E | F | G | H | I | J | K | L | M | N | P | Q | R | S | T | U | V | W | X | Y | Z | URL | | Top |

Oikawa, T. and Yamada, T., Molecular biology of the Ets family of transcription factors, Gene, 303 pp.11-34, 2003. ( IL-1 )

Ono, K. and Han, J., The p38 signal transduction pathway: activation and function, Cellular signalling, 12(1), pp.1-13, 2000. ( IL-1 )

P: A | B | C | D | E | F | G | H | I | J | K | L | M | N | O | Q | R | S | T | U | V | W | X | Y | Z | URL | | Top |
Q: A | B | C | D | E | F | G | H | I | J | K | L | M | N | O | P | R | S | T | U | V | W | X | Y | Z | URL | | Top |

Qin, J., Jiang, Z., Qian, Y., Casanova, J. L. and Li, X., IRAK4 kinase activity is redundant for interleukin-1 (IL-1) receptor-associated kinase phosphorylation and IL-1 responsiveness, The Journal of biological chemistry, 279(25), pp.26748-26753, 2004. ( IL-1 )

Qin, Y., Liu, J., Li, X. and Wei, Q., Preparation and characterization of a single-chain calcineurin-calmodulin complex, Biochimica et biophysica acta, 1747(2), pp.171-178, 2005. ( G-protein )

R: A | B | C | D | E | F | G | H | I | J | K | L | M | N | O | P | Q | S | T | U | V | W | X | Y | Z | URL | | Top |

Raingeaud, J., Whitmarsh, A. J., Barrett, T., Derijard, B. and Davis, R. J., MKK3- and MKK6-regulated gene expression is mediated by the p38 mitogen-activated protein kinase signal transduction pathway, Molecular and cellular biology, 16(3), pp.1247-1255, 1996. ( IL-1 )

Rech, J., Barlat, I., Veyrune, J. L., Vie, A. and Blanchard, J. M., Nuclear import of serum response factor (SRF) requires a short amino-terminal nuclear localization sequence and is independent of the casein kinase II phosphorylation site, Journal of cell science, 107( Pt 11), pp.3029-3036, 1994. ( IL-1 )

Richards, J. P., Bachinger, H. P., Goodman, R. H. and Brennan, R. G., Analysis of the structural properties of cAMP-responsive element-binding protein (CREB) and phosphorylated CREB, The Journal of biological chemistry, 271(23), pp.13716-13727, 1996. ( G-protein )

Rincon, M., Flavell, R. A. and Davis, R. A., The JNK and P38 MAP kinase signaling pathways in T cell-mediated immune responses, Free radical biology & medicine, 28(9), pp.1328-1337, 2000. ( IL-1 )

Roshak, A. K., Callahan, J. F. and Blake, S. M., Small-molecule inhibitors of NF-kappaB for the treatment of inflammatory joint disease, Current Opinion in Pharmacology, 2(3), pp.316-321, 2002. ( IL-1 )

S: A | B | C | D | E | F | G | H | I | J | K | L | M | N | O | P | Q | R | T | U | V | W | X | Y | Z | URL | | Top |

Schaeffer, M., Schneiderbauer, M., Weidler, S., Tavares, R., Warmuth, M., de Vos, G. and Hallek, M., Signaling through a novel domain of gp130 mediates cell proliferation and activation of Hck and Erk kinases, Molecular and cellular biology, 21(23), pp.8068-8081, 2001. ( IL-6 )

Schaffer, M., Eine neue Domane der IL-6 Rezeptor beta-Kette, gp130, vermittelt zellwachstum und die aktivie-rung der kinasen Hck und Erk, 2000. ( IL-6 )

Schmitz, M. L., Bacher, S. and Kracht, M., I kappa B-independent control of NF-kappa B activity by modulatory phosphorylations, Trends in biochemical sciences, 26(3), pp.186-190, 2001. ( IL-1 )

Schulze, H., Ballmaier, M., Welte, K. and Germeshausen, M., Thrombopoietin induces the generation of distinct Stat1, Stat3, Stat5a and Stat5b homo- and heterodimeric complexes with different kinetics in human platelets, Experimental Hematology, 28(3), pp.294-304, 2000. ( TPO )

Shi, Y. and Gaestel, M., In the cellular garden of forking paths: how p38 MAPKs signal for downstream assistance, Biological chemistry, 383(10), pp.1519-1536, 2002. ( IL-1 )

Shi, Y. and Massague, J., Mechanisms of TGF-beta signaling from cell membrane to the nucleus, Cell, 113(6), pp.685-700, 2003. ( TGF-beta )

Streetz, K. L., Luedde, T., Manns, M. P. and Trautwein, C., Interleukin 6 and liver regeneration, Gut, 47(2), pp.309-312, 2000. ( IL-6 )

Stroschein, S. L., Bonni, S., Wrana, J. L. and Luo, K., Smad3 recruits the anaphase-promoting complex for ubiquitination and degradation of SnoN, Genes & development, 15(21), pp.2822-2836, 2001. ( TGF-beta )

Subramaniam, S., Stansberg, C. and Cunningham, C., The interleukin 1 receptor family, Developmental and comparative immunology, 28(5), pp.415-428, 2004. ( IL-1 )

T: A | B | C | D | E | F | G | H | I | J | K | L | M | N | O | P | Q | R | S | U | V | W | X | Y | Z | URL | | Top |

Taga, T., Gp130, a shared signal transducing receptor component for hematopoietic and neuropoietic cytokines, Journal of neurochemistry, 67(1), pp.1-10, 1996. ( IL-6 )

Takaesu, G., Ninomiya-Tsuji, J., Kishida, S., Li, X., Stark, G. R. and Matsumoto, K., Interleukin-1 (IL-1) receptor-associated kinase leads to activation of TAK1 by inducing TAB2 translocation in the IL-1 signaling pathway, Molecular and cellular biology, 21(7), pp.2475-2484, 2001. ( IL-1 )

Tanoue, T. and Nishida, E., Docking interactions in the mitogen-activated protein kinase cascades, Pharmacology & Therapeutics, 93(2-3), pp.193-202, 2002. ( TPO )

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U: A | B | C | D | E | F | G | H | I | J | K | L | M | N | O | P | Q | R | S | T | V | W | X | Y | Z | URL | | Top |

Uhlig, U., Haitsma, J. J., Goldmann, T., Poelma, D. L., Lachmann, B. and Uhlig, S., Ventilation-induced activation of the mitogen-activated protein kinase pathway, The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology, 20(4), pp.946-956, 2002. ( IL-1 )

V: A | B | C | D | E | F | G | H | I | J | K | L | M | N | O | P | Q | R | S | T | U | W | X | Y | Z | URL | | Top |

van Dijk, M. C., Hilkmann, H. and van Blitterswijk, W. J., Platelet-derived growth factor activation of mitogen-activated protein kinase depends on the sequential activation of phosphatidylcholine-specific phospholipase C, protein kinase C-zeta and Raf-1, The Biochemical journal, 325(Pt 2), pp.303-307, 1997. ( PDGF )

Vincent, A. M. and Feldman, E. L., Control of cell survival by IGF signaling pathways, Growth Hormone & IGF Research, 12(4), pp.193-197, 2002. ( IGF-1 )

W: A | B | C | D | E | F | G | H | I | J | K | L | M | N | O | P | Q | R | S | T | U | V | X | Y | Z | URL | | Top |

Wan, Y., Liu, X.and Kirschner, M. W., The anaphase-promoting complex mediates TGF-beta signaling by targeting SnoN for destruction, Molecular Cell, 8(5), pp.1027-1039, 2001. ( TGF-beta )

Wang, C., Deng, L., Hong, M., Akkaraju, G. R., Inoue, J. and Chen, Z. J., TAK1 is a ubiquitin-dependent kinase of MKK and IKK, Nature, 412(6844) pp.346-351, 2001. ( IL-1 )

Wang, T., Zhang, X. and Li, J. J., The role of NF-kappa B in the regulation of cell stress response, International Immunopharmacology, 2(11), pp.1509-1520, 2002. ( IL-1 )

Watts, V. J. and Neve, K. A., Sensitization of adenylate cyclase by Galpha i/o-coupled receptors, Pharmacology & therapeutics, 106(3), pp.405-421, 2005. ( G-protein )

Weston, C. R. and Davis, R. J., The JNK signal transduction pathway, Current opinion in genetics & development, 12(1) pp.14-21, 2002. ( IL-1 )

White, M. F., IRS proteins and the common path to diabetes, American journal of physiology. Endocrinology and metabolism, 283(3), pp.E413-E422, 2002. ( IGF-1 )

X: A | B | C | D | E | F | G | H | I | J | K | L | M | N | O | P | Q | R | S | T | U | V | W | Y | Z | URL | | Top |
Y: A | B | C | D | E | F | G | H | I | J | K | L | M | N | O | P | Q | R | S | T | U | V | W | X | Z | URL | | Top |

Yamamoto, Y. and Gaynor, R. B., IkappaB kinases: key regulators of the NF-kappaB pathway, Trends in biochemical sciences, 29(2), pp.72-79, 2004. ( IL-1 )

Yang, S. H., Sharrocks, A. D. and Whitmarsh, A. J., Transcriptional regulation by the MAP kinase signaling cascades, Gene, 320 pp.3-21, 2003. ( PDGF )

Yonezawa, K., mTOR signaling pathway, Hepatology Research, 30 Suppl, S9-13, 2004. ( PDGF , IGF-1 )

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Zarubin, T. and Han, J., Activation and signaling of the p38 MAP kinase pathway, Cell research, 15(1), pp.11-18, 2005. ( IL-1 )

Zhang, F. and Laiho, M., On and off: proteasome and TGF-beta signaling, Experimental Cell Research, 291(2), pp.275-281, 2003. ( TGF-beta )

URL: A | B | C | D | E | F | G | H | I | J | K | L | M | N | O | P | Q | R | S | T | U | V | W | X | Y | Z | | Top |

Biocarta http://www.biocarta.com/

Biocarta [G-protein] http://www.biocarta.com/pathfiles/h_gpcrPathway.asp

Biocarta [IL-6] http://www.biocarta.com/pathfiles/h_il6Pathway.asp

SPAD (Kyushu University) http://www.grt.kyushu-u.ac.jp/spad/index.html